{"id":2546,"date":"2023-12-17T19:56:36","date_gmt":"2023-12-17T18:56:36","guid":{"rendered":"https:\/\/www.medtechlabs.se\/?post_type=researchleaders&p=2546"},"modified":"2023-12-18T14:38:37","modified_gmt":"2023-12-18T13:38:37","slug":"saul-rodriguez-duenas","status":"publish","type":"researchleaders","link":"https:\/\/www.medtechlabs.se\/sv\/researchleader\/saul-rodriguez-duenas\/","title":{"rendered":"Saul Rodriguez Duenas"},"content":{"rendered":"\n
Programdirekt\u00f6r Kontinuerlig laktatm\u00e4tning och f\u00f6rebyggande av fetal hypoxi under f\u00f6rlossning. Bitr\u00e4dande professor vid avdelningen f\u00f6r elektronik och inbyggda system vid KTH.<\/pre>\n\n\n\n
Vilken forskning utf\u00f6r du vid MedTechLabs?<\/strong><\/p>\n\n\n\n
Foster\u00f6vervakning under f\u00f6rlossningen syftar till att uppt\u00e4cka tidiga tecken p\u00e5 utvecklad hypoxi hos fostret, f\u00f6r att undvika irreversibel v\u00e4vnadsskada. Den foster\u00f6vervakningsmetod som f\u00f6r n\u00e4rvarande anv\u00e4nds under f\u00f6rlossningen best\u00e5r av elektronisk foster\u00f6vervakning med kardiotokografi (CTG). Denna metod utvecklades p\u00e5 1960-talet och har flera begr\u00e4nsningar. D\u00e4rf\u00f6r kompletteras den med blodprovstagning f\u00f6r att uppskatta pH och\/eller laktatkoncentration. Kontinuerlig blodprovstagning p\u00e5 ett foster under f\u00f6rlossningen \u00e4r opraktiskt och d\u00e4rf\u00f6r beh\u00f6vs nya metoder.<\/p>\n\n\n\n
V\u00e5rt m\u00e5l \u00e4r att utveckla ett icke-invasivt inbyggt system f\u00f6r kontinuerlig laktat\u00f6vervakning som \u00e4r baserat p\u00e5 magnetisk induktionsspektroskopi (MIS) och som kan f\u00e4stas p\u00e5 fostrets skalp under f\u00f6rlossningen. MIS-teknik f\u00f6r kontinuerlig \u00f6vervakning av hypoxi \u00e4r en ny metod och flera utmaningar m\u00e5ste l\u00f6sas innan den kan anv\u00e4ndas i f\u00f6rlossningsrum. F\u00f6r det f\u00f6rsta m\u00e5ste man utveckla en miniatyriserad sensorenhet med ultral\u00e5g effekt som uppvisar h\u00f6g k\u00e4nslighet f\u00f6r sm\u00e5 variationer i laktatkoncentrationen. D\u00e4rf\u00f6r kr\u00e4vs en aggressiv anv\u00e4ndning av avancerad mikroelektronik och kretsdesigntekniker med l\u00e5g effekt. Vidare begr\u00e4nsar patients\u00e4kerhetsf\u00f6reskrifterna styrkan p\u00e5 de magnetf\u00e4lt som f\u00e5r anv\u00e4ndas, vilket inneb\u00e4r allvarliga begr\u00e4nsningar f\u00f6r elektronikkonstruktionen. P\u00e5 samma s\u00e4tt begr\u00e4nsar EMC-standarder den oavsiktliga elektromagnetiska str\u00e5lning som en enhet f\u00e5r avge, vilket \u00e4r en viktig aspekt att ta h\u00e4nsyn till f\u00f6r en MIS-enhet som kommer att omges av andra medicinska instrument. Slutligen \u00e4r en robust f\u00e4stmekanism i skalpen av yttersta vikt f\u00f6r att minska m\u00e4tartefakter.<\/p>\n\n\n\n
Vilken inverkan hoppas du f\u00e5 med din forskning?<\/strong><\/p>\n\n\n\n
F\u00f6rlossningsrelaterade hypoxiska skador drabbar motsvarande en till tv\u00e5 skolklasser per \u00e5r enbart i Sverige. Ett framg\u00e5ngsrikt program kommer att bidra till en ny metod f\u00f6r att f\u00f6rb\u00e4ttra patients\u00e4kerheten f\u00f6r kvinnor och deras nyf\u00f6dda barn under f\u00f6rlossningen och minska antalet skadade patienter. Dessutom \u00e4r MIS f\u00f6r kontinuerlig \u00f6vervakning av hypoxi en disruptiv teknik som kan komma till anv\u00e4ndning inom andra medicinska omr\u00e5den, till exempel idrottsmedicin.<\/p>\n\n\n\n
N\u00e4r kan resultat fr\u00e5n denna forskning n\u00e5 patienterna?<\/strong><\/p>\n\n\n\n
Syftet med detta program \u00e4r att demonstrera tekniken i en relevant klinisk milj\u00f6 (teknologisk mognadsniv\u00e5 6). En realistisk tidsram f\u00f6r lansering av en ny medicinteknisk produkt (teknologisk mognadsniv\u00e5 9) \u00e4r cirka +10 \u00e5r.<\/p>\n\n\n\n
Vad \u00e4r din bakgrund och din motivation som forskare?<\/strong><\/p>\n\n\n\n
Jag \u00e4r bitr\u00e4dande professor i elektronik med inriktning mot bioelektronik vid avdelningen f\u00f6r elektronik och inbyggda system p\u00e5 KTH. Jag \u00e4r intresserad av avancerad mikroelektronik f\u00f6r medicinska till\u00e4mpningar med s\u00e4rskilt fokus p\u00e5 miniatyrisering och ultral\u00e5g str\u00f6mf\u00f6rbrukning. Min forskning omfattar design av integrerade kretsar f\u00f6r implanterbar kontinuerlig glukosm\u00e4tning, diagnos av hudmelanomcancer och neuromuskul\u00e4r elektrisk stimulering, allt i samarbete med industrin.<\/p>\n\n\n\n
Kontakta Saul Rodriguez Duenas: saul@kth.se<\/a><\/p>\n\n\n\n


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